Medicine and Health related Information

It is endodermal in origin. It develops as a diverticulum at the junction of foregut and midgut called HEPATIC BUD. This grows cranially and forwards into the mesoderm and septum transversum. A second diverticulum called cystic bud grows from its lower end.

HEPATIC BUD- Divides into right and left branches which divides and redivides and gives rise to cords of liver cells. Later these cords of liver cells are invaded by liver sinusoids which are formed by the breaking of the umblical and vitelline veins and few sinusoids are developed inside. One liver sinusoid which grows bigger in size and connects left umblical vein with the Inferior venacava is called “Ductus Venosus”. Because of this channel blood can pass freely from the left umblical vein in the Inferior venacava. Because of this reason the right umblical vein disappears.

CYSTIC BUD- It gives rise to gall bladder, the cystic duct. The mesenchymal cells give rise to “Von-Kupffer’s Cells”

The lower most part of the hepatic bud forms the bile duct which opens directly on the ventral side but later after the rotation of duodenal loop it comes to open along with pancreatic duct on the postero-medial aspect of duodenum.

The mesoderm of septum transversum gives rise to

a) Glisson’s capsule

b) Falciform ligament

c) Triangular ligament

d) Coronary ligament.