Medicine and Health related Information

Pancreas develops from endoderm by 2 diverticulum called- Ventral pancreatic bud

Dorsal pancreatic bud

VENTRAL PANCREATIC BUD- It develops on the ventral side caudal to the hepatic bud and communicates with it.

DORSAL PANCREATIC BUD- It develops on the dorsal side and grows dorsally into the dorsal mesentry.

After the rotation of the duodenal loop, the ventral and dorsal buds come in contact with one another and lies within the concavity of duodenum.

The ventral bud gives rise to

a) Lower end of the head.

b) Uncinate process of the pancreas.

The dorsal bud gives rise to

a) Upper part of the head, whole of the body and tail of the pancreas. Secretory elements of pancreas are formed by the proliferation of primitive duct. Islets of Langerhans are also derived from the primitive duct system.

DUCT SYSTEM- The main pancreatic duct of wirsing is formed by the wholes of- Duct of ventral bud.

Distal part of the duct of dorsal bud along with bile duct forms “Hepatic Pancreatic Ampulla” which opens into major duodenal papilla at the junction of foregut and midgut.

Accessory pancreatic duct of Santotini- It is formed by the proximal part of duct of dorsal bud , usually disappears. If present it opens onto the minor duodenal papilla which is present 2cm above the major duodenal papilla.